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The transcription factor Tfcp2l1 promotes primordial germ cell–like cell specification of pluripotent stem cells
Primordial germ cells (PGCs) are common ancestors of all germline cells. However, mechanistic understanding of how PGC specification occurs is limited. Here, we identified transcription factor CP2-like 1 (Tfcp2l1), an important pluripotency factor, as a pivotal factor for PGC-like cell (PGCLC) speci...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8517209/ https://www.ncbi.nlm.nih.gov/pubmed/34555410 http://dx.doi.org/10.1016/j.jbc.2021.101217 |