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The transcription factor Tfcp2l1 promotes primordial germ cell–like cell specification of pluripotent stem cells

Primordial germ cells (PGCs) are common ancestors of all germline cells. However, mechanistic understanding of how PGC specification occurs is limited. Here, we identified transcription factor CP2-like 1 (Tfcp2l1), an important pluripotency factor, as a pivotal factor for PGC-like cell (PGCLC) speci...

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Detalles Bibliográficos
Autores principales: Zhang, Meng, Ji, Junxiang, Wang, Xiaoxiao, Zhang, Xinbao, Zhang, Yan, Li, Yuting, Wang, Xin, Li, Xiaofeng, Ban, Qian, Ye, Shou-Dong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8517209/
https://www.ncbi.nlm.nih.gov/pubmed/34555410
http://dx.doi.org/10.1016/j.jbc.2021.101217

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