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Vitamin D signaling inhibits HBV activity by directly targeting the HBV core promoter

Clinical and epidemiological studies support a role for vitamin D in suppressing hepatitis B virus (HBV). This antiviral role of vitamin D is widely attributed to vitamin D receptor (VDR)/retinoid X receptor–mediated regulation of host immunomodulatory genes through vitamin D response elements (VDRE...

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Detalles Bibliográficos
Autores principales: Ahluwalia, Shivaksh, Choudhary, Divya, Tyagi, Purnima, Kumar, Vijay, Vivekanandan, Perumal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8517215/
https://www.ncbi.nlm.nih.gov/pubmed/34562448
http://dx.doi.org/10.1016/j.jbc.2021.101233