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The MID1 Protein: A Promising Therapeutic Target in Huntington’s Disease

Huntington’s disease (HD) is caused by an expansion mutation of a CAG repeat in exon 1 of the huntingtin (HTT) gene, that encodes an expanded polyglutamine tract in the HTT protein. HD is characterized by progressive psychiatric and cognitive symptoms associated with a progressive movement disorder....

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Detalles Bibliográficos
Autores principales: Heinz, Annika, Schilling, Judith, van Roon-Mom, Willeke, Krauß, Sybille
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8517220/
https://www.ncbi.nlm.nih.gov/pubmed/34659371
http://dx.doi.org/10.3389/fgene.2021.761714