A Key Silencing Histone Mark on Chromatin Is Lost When Colorectal Adenocarcinoma Cells Are Depleted of Methionine by Methionine γ-Lyase

Methionine is an essential amino acid used, beyond protein synthesis, for polyamine formation and DNA/RNA/protein methylation. Cancer cells require particularly high methionine supply for their homeostasis. A successful approach for decreasing methionine concentration is based on the systemic delive...

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Detalles Bibliográficos
Autores principales: Raboni, Samanta, Montalbano, Serena, Stransky, Stephanie, Garcia, Benjamin A., Buschini, Annamaria, Bettati, Stefano, Sidoli, Simone, Mozzarelli, Andrea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Molecular Biosciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8517235/
https://www.ncbi.nlm.nih.gov/pubmed/34660696
http://dx.doi.org/10.3389/fmolb.2021.735303

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8517235/
https://www.ncbi.nlm.nih.gov/pubmed/34660696
http://dx.doi.org/10.3389/fmolb.2021.735303

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