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A Key Silencing Histone Mark on Chromatin Is Lost When Colorectal Adenocarcinoma Cells Are Depleted of Methionine by Methionine γ-Lyase
Methionine is an essential amino acid used, beyond protein synthesis, for polyamine formation and DNA/RNA/protein methylation. Cancer cells require particularly high methionine supply for their homeostasis. A successful approach for decreasing methionine concentration is based on the systemic delive...
Autores principales: | Raboni, Samanta, Montalbano, Serena, Stransky, Stephanie, Garcia, Benjamin A., Buschini, Annamaria, Bettati, Stefano, Sidoli, Simone, Mozzarelli, Andrea |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8517235/ https://www.ncbi.nlm.nih.gov/pubmed/34660696 http://dx.doi.org/10.3389/fmolb.2021.735303 |
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