Common Statin Intolerance Variants in ABCB1 and LILRB5 Show Synergistic Effects on Statin Response: An Observational Study Using Electronic Health Records

Background: Statin intolerance impacts approximately 10% of statin users, with side effects ranging from mild myalgia to extreme intolerance resulting in myopathy and rhabdomyolysis. Statin intolerance results in poor adherence to therapy and can impact statin efficacy. Many genetic variants are ass...

Descripción completa

Detalles Bibliográficos
Autores principales: Melhem, Alaa’ Lutfi, Chourasia, Mehul Kumar, Bigossi, Margherita, Maroteau, Cyrielle, Taylor, Alasdair, Pola, Roberto, Dawed, Adem Y., Tornio, Aleksi, Palmer, Colin N. A., Siddiqui, Moneeza K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Genetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8517257/
https://www.ncbi.nlm.nih.gov/pubmed/34659336
http://dx.doi.org/10.3389/fgene.2021.713181

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8517257/
https://www.ncbi.nlm.nih.gov/pubmed/34659336
http://dx.doi.org/10.3389/fgene.2021.713181

Ejemplares similares