Dual Regulation of Tank Binding Kinase 1 by BRG1 in Hepatocytes Contributes to Reactive Oxygen Species Production

Excessive accumulation of reactive oxygen species (ROS) is considered a major culprit for the pathogenesis of non-alcoholic fatty liver disease (NAFLD). We have previously shown that deletion of Brahma related gene 1 (BRG1) mitigated NAFLD in mice in part by attenuating ROS production in hepatocyte....

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Detalles Bibliográficos
Autores principales: Lv, Fangqiao, Shao, Tinghui, Xue, Yujia, Miao, Xiulian, Guo, Yan, Wang, Yutong, Xu, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8517266/
https://www.ncbi.nlm.nih.gov/pubmed/34660604
http://dx.doi.org/10.3389/fcell.2021.745985

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8517266/
https://www.ncbi.nlm.nih.gov/pubmed/34660604
http://dx.doi.org/10.3389/fcell.2021.745985

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