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Modified UCN2 peptide treatment improves skeletal muscle mass and function in mouse models of obesity‐induced insulin resistance

BACKGROUND: Type 2 diabetes and obesity are often seen concurrently with skeletal muscle wasting, leading to further derangements in function and metabolism. Muscle wasting remains an unmet need for metabolic disease, and new approaches are warranted. The neuropeptide urocortin 2 (UCN2) and its rece...

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Detalles Bibliográficos
Autores principales: Borg, Melissa L., Massart, Julie, De Castro Barbosa, Thais, Archilla‐Ortega, Adrià, Smith, Jonathon A.B., Lanner, Johanna T., Alsina‐Fernandez, Jorge, Yaden, Benjamin, Culver, Alexander E., Karlsson, Håkan K.R., Brozinick, Joseph T., Zierath, Juleen R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8517345/
https://www.ncbi.nlm.nih.gov/pubmed/34342159
http://dx.doi.org/10.1002/jcsm.12746