Targeting interleukin‐1 for reversing fat browning and muscle wasting in infantile nephropathic cystinosis

BACKGROUND: Ctns ( −/− ) mice, a mouse model of infantile nephropathic cystinosis, exhibit hypermetabolism with adipose tissue browning and profound muscle wasting. Inflammatory cytokines such as interleukin (IL)‐1 trigger inflammatory cascades and may be an important cause for cachexia. We employed...

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Detalles Bibliográficos
Autores principales: Cheung, Wai W., Hao, Sheng, Zheng, Ronghao, Wang, Zhen, Gonzalez, Alex, Zhou, Ping, Hoffman, Hal M., Mak, Robert H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8517356/
https://www.ncbi.nlm.nih.gov/pubmed/34196133
http://dx.doi.org/10.1002/jcsm.12744

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8517356/
https://www.ncbi.nlm.nih.gov/pubmed/34196133
http://dx.doi.org/10.1002/jcsm.12744

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