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Growth hormone secretagogue receptor‐1a mediates ghrelin's effects on attenuating tumour‐induced loss of muscle strength but not muscle mass

BACKGROUND: Ghrelin may ameliorate cancer cachexia (CC) by preventing anorexia, muscle, and fat loss. However, the mechanisms mediating these effects are not fully understood. This study characterizes the pathways involved in muscle mass and strength loss in the Lewis lung carcinoma (LLC)‐induced ca...

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Detalles Bibliográficos
Autores principales: Liu, Haiming, Zang, Pu, Lee, Ian (In‐gi), Anderson, Barbara, Christiani, Anthony, Strait‐Bodey, Lena, Breckheimer, Beatrice A., Storie, Mackenzie, Tewnion, Alison, Krumm, Kora, Li, Theresa, Irwin, Brynn, Garcia, Jose M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8517358/
https://www.ncbi.nlm.nih.gov/pubmed/34264027
http://dx.doi.org/10.1002/jcsm.12743