HIV reservoir quantification by five-target multiplex droplet digital PCR

Most latent human immunodeficiency virus (HIV) proviruses are defective and cannot produce infectious virions. Thus, the number of HIV proviruses with intact genomes is a relevant clinical parameter to assess therapies for HIV cure. We describe high-molecular-weight DNA isolation, followed by restri...

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Detalles Bibliográficos
Autores principales: Levy, Claire N., Hughes, Sean M., Roychoudhury, Pavitra, Amstuz, Chelsea, Zhu, Haiying, Huang, Meei-Li, Lehman, Dara A., Jerome, Keith R., Hladik, Florian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Protocol
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8517383/
https://www.ncbi.nlm.nih.gov/pubmed/34693363
http://dx.doi.org/10.1016/j.xpro.2021.100885

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8517383/
https://www.ncbi.nlm.nih.gov/pubmed/34693363
http://dx.doi.org/10.1016/j.xpro.2021.100885

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