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HIV reservoir quantification by five-target multiplex droplet digital PCR
Most latent human immunodeficiency virus (HIV) proviruses are defective and cannot produce infectious virions. Thus, the number of HIV proviruses with intact genomes is a relevant clinical parameter to assess therapies for HIV cure. We describe high-molecular-weight DNA isolation, followed by restri...
Autores principales: | Levy, Claire N., Hughes, Sean M., Roychoudhury, Pavitra, Amstuz, Chelsea, Zhu, Haiying, Huang, Meei-Li, Lehman, Dara A., Jerome, Keith R., Hladik, Florian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8517383/ https://www.ncbi.nlm.nih.gov/pubmed/34693363 http://dx.doi.org/10.1016/j.xpro.2021.100885 |
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