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Altered Frequency and Phenotype of HLA-G-Expressing DC-10 in Type 1 Diabetes Patients at Onset and in Subjects at Risk to Develop the Disease

Type 1 diabetes (T1D) is a chronic autoimmune disease resulting in progressive destruction of β-cells. Several factors affecting lymphocyte and antigen-presenting cells, including dendritic cells (DCs), contribute to defective maintenance of tolerance in T1D. DC-10 are a subset of human DCs involved...

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Detalles Bibliográficos
Autores principales: Amodio, Giada, Mandelli, Alessandra, Curto, Rosalia, Rancoita, Paola M. V., Stabilini, Angela, Bonfanti, Riccardo, de Pellegrin, Maurizio, Bosi, Emanuele, Di Serio, Clelia, Battaglia, Manuela, Gregori, Silvia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8517474/
https://www.ncbi.nlm.nih.gov/pubmed/34659254
http://dx.doi.org/10.3389/fimmu.2021.750162