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Transcriptional landscape associated with TNBC resistance to neoadjuvant chemotherapy revealed by single-cell RNA-seq

Triple-negative breast cancer (TNBC) resistance to neoadjuvant chemotherapy (NAC) represents a major clinical challenge; therefore, delineating tumor heterogeneity can provide novel insight into resistance mechanisms and potential therapeutic targets. Herein, we identified the transcriptional landsc...

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Detalles Bibliográficos
Autores principales: Vishnubalaji, Radhakrishnan, Alajez, Nehad M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8517543/
https://www.ncbi.nlm.nih.gov/pubmed/34703883
http://dx.doi.org/10.1016/j.omto.2021.09.002