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Pathogen‐induced inflammation is attenuated by the iminosugar MON‐DNJ via modulation of the unfolded protein response

Sepsis is a life‐threatening condition involving a dysregulated immune response to infectious agents that cause injury to host tissues and organs. Current treatments are limited to early administration of antibiotics and supportive care. While appealing, the strategy of targeted inhibition of indivi...

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Detalles Bibliográficos
Autores principales: Sayce, Andrew C., Martinez, Fernando O., Tyrrell, Beatrice E., Perera, Nilanka, Hill, Michelle L., Dwek, Raymond A., Miller, Joanna L., Zitzmann, Nicole
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8517592/
https://www.ncbi.nlm.nih.gov/pubmed/34287854
http://dx.doi.org/10.1111/imm.13393