Schlafen 11 expression in human acute leukemia cells with gain-of-function mutations in the interferon-JAK signaling pathway

Schlafen11 (SLFN11) is referred to as interferon (IFN)-inducible. Based on cancer genomic databases, we identified human acute myeloid and lymphoblastic leukemia cells with gain-of-function mutations in the Janus kinase (JAK) family as exhibiting high SLFN11 expression. In these cells, the clinical...

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Detalles Bibliográficos
Autores principales: Murai, Yasuhisa, Jo, Ukhyun, Murai, Junko, Fukuda, Shinsaku, Takebe, Naoko, Pommier, Yves
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8517841/
https://www.ncbi.nlm.nih.gov/pubmed/34693224
http://dx.doi.org/10.1016/j.isci.2021.103173

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8517841/
https://www.ncbi.nlm.nih.gov/pubmed/34693224
http://dx.doi.org/10.1016/j.isci.2021.103173

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