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Germline polymorphisms and alternative splicing of human immunoglobulin light chain genes
Inference of germline polymorphisms in immunoglobulin genes from B cell receptor repertoires is complicated by somatic hypermutations, sequencing/PCR errors, and by varying length of reference alleles. The light chain inference is particularly challenging owing to large gene duplications and absence...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8517844/ https://www.ncbi.nlm.nih.gov/pubmed/34693229 http://dx.doi.org/10.1016/j.isci.2021.103192 |