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Germline polymorphisms and alternative splicing of human immunoglobulin light chain genes

Inference of germline polymorphisms in immunoglobulin genes from B cell receptor repertoires is complicated by somatic hypermutations, sequencing/PCR errors, and by varying length of reference alleles. The light chain inference is particularly challenging owing to large gene duplications and absence...

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Detalles Bibliográficos
Autores principales: Mikocziova, Ivana, Peres, Ayelet, Gidoni, Moriah, Greiff, Victor, Yaari, Gur, Sollid, Ludvig M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8517844/
https://www.ncbi.nlm.nih.gov/pubmed/34693229
http://dx.doi.org/10.1016/j.isci.2021.103192