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Germline polymorphisms and alternative splicing of human immunoglobulin light chain genes

Inference of germline polymorphisms in immunoglobulin genes from B cell receptor repertoires is complicated by somatic hypermutations, sequencing/PCR errors, and by varying length of reference alleles. The light chain inference is particularly challenging owing to large gene duplications and absence...

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Detalles Bibliográficos
Autores principales:	Mikocziova, Ivana, Peres, Ayelet, Gidoni, Moriah, Greiff, Victor, Yaari, Gur, Sollid, Ludvig M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8517844/ https://www.ncbi.nlm.nih.gov/pubmed/34693229 http://dx.doi.org/10.1016/j.isci.2021.103192

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