Mechanisms of abemaciclib, a CDK4/6 inhibitor, induced apoptotic cell death in prostate cancer cells in vitro

The therapeutic effects of abemaciclib (ABE), an inhibitor of cyclin- dependent kinases (CDK) 4/6, on the proliferation of two types of prostate cancer (PC) cells were revealed. In this study, in vitro cytotoxic and apoptotic effects of ABE on metastatic castration-resistant prostate cancer (mCRPC)...

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Detalles Bibliográficos
Autores principales: Guney Eskiler, Gamze, Deveci Ozkan, Asuman, Haciefendi, Ayten, Bilir, Cemil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2021
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8517924/
https://www.ncbi.nlm.nih.gov/pubmed/34649150
http://dx.doi.org/10.1016/j.tranon.2021.101243

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8517924/
https://www.ncbi.nlm.nih.gov/pubmed/34649150
http://dx.doi.org/10.1016/j.tranon.2021.101243

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