Nuclear localization dictates hepatocarcinogenesis suppression by glycine N-methyltransferase

BACKGROUND: GNMT (glycine N-methyltransferase) is a tumor suppressor gene, but the mechanisms mediating its suppressive activity are not entirely known. METHODS: We investigated the oncosuppressive mechanisms of GNMT in human hepatocellular carcinoma (HCC). GNMT mRNA and protein levels were evaluate...

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Detalles Bibliográficos
Autores principales: Simile, Maria M., Cigliano, Antonio, Paliogiannis, Panagiotis, Daino, Lucia, Manetti, Roberto, Feo, Claudio F., Calvisi, Diego F., Feo, Francesco, Pascale, Rosa M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2021
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8517931/
https://www.ncbi.nlm.nih.gov/pubmed/34649149
http://dx.doi.org/10.1016/j.tranon.2021.101239

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8517931/
https://www.ncbi.nlm.nih.gov/pubmed/34649149
http://dx.doi.org/10.1016/j.tranon.2021.101239

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