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Synergistic killing effects of PD-L1-CAR T cells and colorectal cancer stem cell-dendritic cell vaccine-sensitized T cells in ALDH1-positive colorectal cancer stem cells

Cancer stem cells (CSCs) are characterized by self-renewal and unlimited proliferation, providing a basis for tumor occurrence, metastasis, and recurrence. Because CSCs are highly resistant to conventional chemotherapy and radiotherapy, various immunotherapies, particularly chimeric antigen receptor...

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Detalles Bibliográficos
Autores principales: Liu, Liu, Liu, Yuanyuan, Xia, Yang, Wang, Guanlong, Zhang, Xiushan, Zhang, Huan, Xu, Yang, Yuan, Yuan, Liu, Shangquan, Wang, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8517999/
https://www.ncbi.nlm.nih.gov/pubmed/34659553
http://dx.doi.org/10.7150/jca.62123