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Shikonin suppresses the epithelial-to-mesenchymal transition by downregulating NHE1 in bladder cancer cells

Shikonin (SK) is the major bioactive component extracted from the roots of Lithospermum erythrorhizon with anticancer activity. SK could inhibit the epithelial-to-mesenchymal transition (EMT) of cancer cells. However, the underlying mechanism is elusive. In the present study, the inhibitory activiti...

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Detalles Bibliográficos
Autores principales: Mo, Lijun, Xu, Lili, Jia, Min, Su, Bijia, Hu, Yaolong, Hu, Zhiming, Li, Hongwei, Zhao, Chenye, Zhao, Zhenlin, Li, Jinlong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8518005/
https://www.ncbi.nlm.nih.gov/pubmed/34659570
http://dx.doi.org/10.7150/jca.63429