An Optimized Chemical-Genetic Method for Cell-Specific Metabolic Labeling of RNA

Tissues and organs are composed of diverse cell types, which poses a major challenge for cell-specific gene expression profiling. Current metabolic labeling methods rely on the inability of mammalian cells to incorporate exogenous pyrimidine analogs, which are then co-opted by ectopically-expressed...

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Detalles Bibliográficos
Autores principales: Nainar, Sarah, Cuthbert, Bonnie, Lim, Nathan M., England, Whitney E., Ke, Ke, Sophal, Kanika, Quechol, Robert, Mobley, David L., Goulding, Celia W., Spitale, Robert C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8518020/
https://www.ncbi.nlm.nih.gov/pubmed/32015544
http://dx.doi.org/10.1038/s41592-019-0726-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8518020/
https://www.ncbi.nlm.nih.gov/pubmed/32015544
http://dx.doi.org/10.1038/s41592-019-0726-y

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