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Three‐level hybrid modeling for systematic optimization of biocatalytic synthesis: α‐glucosyl glycerol production by enzymatic trans‐glycosylation from sucrose
Mechanism‐based kinetic models are rigorous tools to analyze enzymatic reactions, but their extension to actual conditions of the biocatalytic synthesis can be difficult. Here, we demonstrate (mechanistic‐empirical) hybrid modeling for systematic optimization of the sucrose phosphorylase‐catalyzed g...
Autores principales: | Sigg, Alexander, Klimacek, Mario, Nidetzky, Bernd |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8518044/ https://www.ncbi.nlm.nih.gov/pubmed/34232503 http://dx.doi.org/10.1002/bit.27878 |
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