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Radiolabelled Cyclic Bisarylmercury: High Chemical and in vivo Stability for Theranostics

We show the synthesis of an in vivo stable mercury compound with functionality suitable for radiopharmaceuticals. The designed cyclic bisarylmercury was based on the water tolerance of organomercurials, higher bond dissociation energy of Hg−Ph to Hg−S, and the experimental evidence that acyclic stru...

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Detalles Bibliográficos
Autores principales: Gilpin, Ian Moore F., Ullrich, Martin, Wünsche, Thomas, Zarschler, Kristof, Lebeda, Ondřej, Pietzsch, Jens, Pietzsch, Hans‐Jürgen, Walther, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8518081/
https://www.ncbi.nlm.nih.gov/pubmed/33949125
http://dx.doi.org/10.1002/cmdc.202100131