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Tetrahydroquinoline/4,5‐Dihydroisoxazole Molecular Hybrids as Inhibitors of Breast Cancer Resistance Protein (BCRP/ABCG2)

Multidrug resistance (MDR) is one of the major factors in the failure of many chemotherapy approaches. In cancer cells, MDR is mainly associated with the expression of ABC transporters such as P‐glycoprotein, MRP1 and ABCG2. Despite major efforts to develop new selective and potent inhibitors of ABC...

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Detalles Bibliográficos
Autores principales: Vesga, Luis C., Kronenberger, Thales, Tonduru, Arun Kumar, Kita, Diogo Henrique, Zattoni, Ingrid Fatima, Bernal, Cristian Camilo, Bohórquez, Arnold R. Romero, Mendez‐Sánchez, Stelia Carolina, Ambudkar, Suresh V., Valdameri, Glaucio, Poso, Antti
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8518119/
https://www.ncbi.nlm.nih.gov/pubmed/33844464
http://dx.doi.org/10.1002/cmdc.202100188