Benchmarking sequencing methods and tools that facilitate the study of alternative polyadenylation

BACKGROUND: Alternative cleavage and polyadenylation (APA), an RNA processing event, occurs in over 70% of human protein-coding genes. APA results in mRNA transcripts with distinct 3′ ends. Most APA occurs within 3′ UTRs, which harbor regulatory elements that can impact mRNA stability, translation,...

Descripción completa

Detalles Bibliográficos
Autores principales: Shah, Ankeeta, Mittleman, Briana E., Gilad, Yoav, Li, Yang I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8518154/
https://www.ncbi.nlm.nih.gov/pubmed/34649612
http://dx.doi.org/10.1186/s13059-021-02502-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8518154/
https://www.ncbi.nlm.nih.gov/pubmed/34649612
http://dx.doi.org/10.1186/s13059-021-02502-z

Ejemplares similares