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Short single-stranded DNAs with putative non-canonical structures comprise a new class of plasma cell-free DNA

BACKGROUND: Cell-free DNA (cfDNA), which is extracellular DNA present in the circulating plasma and other body fluids, is currently investigated as a minimally invasive, highly informative biomarker. While nucleosome-sized cfDNA fragments have been investigated intensively, shorter DNA fragments in...

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Detalles Bibliográficos
Autores principales: Hisano, Osamu, Ito, Takashi, Miura, Fumihito
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8518174/
https://www.ncbi.nlm.nih.gov/pubmed/34649537
http://dx.doi.org/10.1186/s12915-021-01160-8