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Genetic and process engineering strategies for enhanced recombinant N-glycoprotein production in bacteria

BACKGROUND: The production of N-linked glycoproteins in genetically amenable bacterial hosts offers great potential for reduced cost, faster/simpler bioprocesses, greater customisation, and utility for distributed manufacturing of glycoconjugate vaccines and glycoprotein therapeutics. Efforts to opt...

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Detalles Bibliográficos
Autores principales: Pratama, Fenryco, Linton, Dennis, Dixon, Neil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8518210/
https://www.ncbi.nlm.nih.gov/pubmed/34649588
http://dx.doi.org/10.1186/s12934-021-01689-x