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HBeAg mediates inflammatory functions of macrophages by TLR2 contributing to hepatic fibrosis

BACKGROUND: We and others have confirmed activation of macrophages plays a critical role in liver injury and fibrogenesis during HBV infection. And we have also proved HBeAg can obviously induce the production of macrophage inflammatory cytokines compared with HBsAg and HBcAg. However, the receptor...

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Detalles Bibliográficos
Autores principales: Xie, Xiaoyu, Lv, Huanran, Liu, Chenxi, Su, Xiaonan, Yu, Zhen, Song, Shouyang, Bian, Hongjun, Tian, Miaomiao, Qin, Chengyong, Qi, Jianni, Zhu, Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8518250/
https://www.ncbi.nlm.nih.gov/pubmed/34649530
http://dx.doi.org/10.1186/s12916-021-02085-3