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White matter injury but not germinal matrix hemorrhage induces elevated osteopontin expression in human preterm brains

Osteopontin (OPN) is a matricellular protein that mediates various physiological functions and is implicated in neuroinflammation, myelination, and perinatal brain injury. However, its expression in association with brain injury in preterm infants is unexplored. Here we examined the expression of OP...

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Detalles Bibliográficos
Autores principales: Nilsson, Gisela, Baburamani, Ana A., Rutherford, Mary A., Zhu, Changlian, Mallard, Carina, Hagberg, Henrik, Vontell, Regina, Wang, Xiaoyang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8518254/
https://www.ncbi.nlm.nih.gov/pubmed/34654477
http://dx.doi.org/10.1186/s40478-021-01267-7