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Tailored graphical lasso for data integration in gene network reconstruction

BACKGROUND: Identifying gene interactions is a topic of great importance in genomics, and approaches based on network models provide a powerful tool for studying these. Assuming a Gaussian graphical model, a gene association network may be estimated from multiomic data based on the non-zero entries...

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Detalles Bibliográficos
Autores principales: Lingjærde, Camilla, Lien, Tonje G., Borgan, Ørnulf, Bergholtz, Helga, Glad, Ingrid K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8518261/
https://www.ncbi.nlm.nih.gov/pubmed/34654363
http://dx.doi.org/10.1186/s12859-021-04413-z