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Tailored graphical lasso for data integration in gene network reconstruction
BACKGROUND: Identifying gene interactions is a topic of great importance in genomics, and approaches based on network models provide a powerful tool for studying these. Assuming a Gaussian graphical model, a gene association network may be estimated from multiomic data based on the non-zero entries...
Autores principales: | Lingjærde, Camilla, Lien, Tonje G., Borgan, Ørnulf, Bergholtz, Helga, Glad, Ingrid K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8518261/ https://www.ncbi.nlm.nih.gov/pubmed/34654363 http://dx.doi.org/10.1186/s12859-021-04413-z |
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