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CDKN2B-AS1 participates in high glucose-induced apoptosis and fibrosis via NOTCH2 through functioning as a miR-98-5p decoy in human podocytes and renal tubular cells

BACKGROUND: Diabetic nephropathy (DN) is the most common causes of end-stage renal disease. Long non-coding RNA cyclin-dependent kinase inhibitor 2B antisense RNA 1 (CDKN2B-AS1) is connected with the development of DN, but the role of CDKN2B-AS1 in DN has not been entirely elucidated. METHODS: Quant...

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Detalles Bibliográficos
Autores principales: Xiao, Min, Bai, Shoujun, Chen, Jing, Li, Yaxi, Zhang, Shu, Hu, Zhao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8518318/
https://www.ncbi.nlm.nih.gov/pubmed/34649592
http://dx.doi.org/10.1186/s13098-021-00725-5