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Label-free separation of neuroblastoma patient-derived xenograft (PDX) cells from hematopoietic progenitor cell products by acoustophoresis

BACKGROUND: Graft-contaminating tumor cells correlate with inferior outcome in high-risk neuroblastoma patients undergoing hematopoietic stem cell transplantation and can contribute to relapse. Motivated by the potential therapeutic benefit of tumor cell removal as well as the high prognostic and di...

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Detalles Bibliográficos
Autores principales: Olm, Franziska, Panse, Lena, Dykes, Josefina H., Bexell, Daniel, Laurell, Thomas, Scheding, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8518319/
https://www.ncbi.nlm.nih.gov/pubmed/34654486
http://dx.doi.org/10.1186/s13287-021-02612-2