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DZIP1 regulates mammalian cardiac valve development through a Cby1‐β‐catenin mechanism

BACKGROUND: Mitral valve prolapse (MVP) is a common and progressive cardiovascular disease with developmental origins. How developmental errors contribute to disease pathogenesis are not well understood. RESULTS: A multimeric complex was identified that consists of the MVP gene Dzip1, Cby1, and β‐ca...

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Detalles Bibliográficos
Autores principales: Guo, Lilong, Beck, Tyler, Fulmer, Diana, Ramos‐Ortiz, Sandra, Glover, Janiece, Wang, Christina, Moore, Kelsey, Gensemer, Cortney, Morningstar, Jordan, Moore, Reece, Schott, Jean‐Jacques, Le Tourneau, Thierry, Koren, Natalie, Norris, Russell A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8518365/
https://www.ncbi.nlm.nih.gov/pubmed/33811421
http://dx.doi.org/10.1002/dvdy.342