Loss‐of‐Function Genetic Screening Identifies Aldolase A as an Essential Driver for Liver Cancer Cell Growth Under Hypoxia

BACKGROUND AND AIMS: Hypoxia is a common feature of the tumor microenvironment (TME), which promotes tumor progression, metastasis, and therapeutic drug resistance through a myriad of cell activities in tumor and stroma cells. While targeting hypoxic TME is emerging as a promising strategy for treat...

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Detalles Bibliográficos
Autores principales: Niu, Yi, Lin, Ziyou, Wan, Arabella, Sun, Lei, Yan, Shijia, Liang, Heng, Zhan, Siyue, Chen, Dongshi, Bu, Xianzhang, Liu, Peiqing, Chen, Ceshi, He, Weiling, Lu, Xiongbin, Wan, Guohui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8518375/
https://www.ncbi.nlm.nih.gov/pubmed/33813748
http://dx.doi.org/10.1002/hep.31846

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8518375/
https://www.ncbi.nlm.nih.gov/pubmed/33813748
http://dx.doi.org/10.1002/hep.31846

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