Identification of a Bromodomain‐like Region in 15‐Lipoxygenase‐1 Explains Its Nuclear Localization

Lipoxygenase (LOX) activity provides oxidative lipid metabolites, which are involved in inflammatory disorders and tumorigenesis. Activity‐based probes to detect the activity of LOX enzymes in their cellular context provide opportunities to explore LOX biology and LOX inhibition. Here, we developed...

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Detalles Bibliográficos
Autores principales: Chen, Deng, Xiao, Zhangping, Guo, Hao, Gogishvili, Dea, Setroikromo, Rita, van der Wouden, Petra E., Dekker, Frank J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8518382/
https://www.ncbi.nlm.nih.gov/pubmed/34388301
http://dx.doi.org/10.1002/anie.202106968

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8518382/
https://www.ncbi.nlm.nih.gov/pubmed/34388301
http://dx.doi.org/10.1002/anie.202106968

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