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Stereoselective methadone disposition after administration of racemic methadone to anesthetized Shetland ponies assessed by capillary electrophoresis

The enantioselectivity of the pharmacokinetics of methadone was investigated in anesthetized Shetland ponies after a single intravenous (0.5 mg/kg methadone hydrochloride; n = 6) or constant rate infusion (0.25 mg/kg bolus followed by 0.25 mg/kg/h methadone hydrochloride; n = 3) administration of ra...

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Detalles Bibliográficos
Autores principales: Sandbaumhüter, Friederike A., Gittel, Claudia, Larenza‐Menzies, M. Paula, Theurillat, Regula, Thormann, Wolfgang, Braun, Christina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8518386/
https://www.ncbi.nlm.nih.gov/pubmed/33978252
http://dx.doi.org/10.1002/elps.202100115