Synthesis and Biological Evaluation of Dantrolene‐Like Hydrazide and Hydrazone Analogues as Multitarget Agents for Neurodegenerative Diseases

Dantrolene, a drug used for the management of malignant hyperthermia, had been recently evaluated for prospective repurposing as multitarget agent for neurodegenerative syndromes, including Alzheimer's disease (AD). Herein, twenty‐one dantrolene‐like hydrazide and hydrazone analogues were synth...

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Detalles Bibliográficos
Autores principales: Bolognino, Isabella, Giangregorio, Nicola, Tonazzi, Annamaria, Martínez, Antón L., Altomare, Cosimo D., Loza, María I., Sablone, Sara, Cellamare, Saverio, Catto, Marco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Full Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8518391/
https://www.ncbi.nlm.nih.gov/pubmed/34047061
http://dx.doi.org/10.1002/cmdc.202100209

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8518391/
https://www.ncbi.nlm.nih.gov/pubmed/34047061
http://dx.doi.org/10.1002/cmdc.202100209

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