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Synthesis and Biological Evaluation of Dantrolene‐Like Hydrazide and Hydrazone Analogues as Multitarget Agents for Neurodegenerative Diseases
Dantrolene, a drug used for the management of malignant hyperthermia, had been recently evaluated for prospective repurposing as multitarget agent for neurodegenerative syndromes, including Alzheimer's disease (AD). Herein, twenty‐one dantrolene‐like hydrazide and hydrazone analogues were synth...
Autores principales: | Bolognino, Isabella, Giangregorio, Nicola, Tonazzi, Annamaria, Martínez, Antón L., Altomare, Cosimo D., Loza, María I., Sablone, Sara, Cellamare, Saverio, Catto, Marco |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8518391/ https://www.ncbi.nlm.nih.gov/pubmed/34047061 http://dx.doi.org/10.1002/cmdc.202100209 |
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