Valproic Acid Enhanced Temozolomide-Induced Anticancer Activity in Human Glioma Through the p53–PUMA Apoptosis Pathway

Glioblastoma (GBM), the most lethal type of brain tumor in adults, has considerable cellular heterogeneity. The standard adjuvant chemotherapeutic agent for GBM, temozolomide (TMZ), has a modest response rate due to the development of drug resistance. Multiple studies have shown that valproic acid (...

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Detalles Bibliográficos
Autores principales: Tsai, Hong-Chieh, Wei, Kuo-Chen, Chen, Pin-Yuan, Huang, Chiung-Yin, Chen, Ko-Ting, Lin, Ya-Jui, Cheng, Hsiao-Wei, Chen, Yi-Rou, Wang, Hsiang-Tsui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8518553/
https://www.ncbi.nlm.nih.gov/pubmed/34660288
http://dx.doi.org/10.3389/fonc.2021.722754

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8518553/
https://www.ncbi.nlm.nih.gov/pubmed/34660288
http://dx.doi.org/10.3389/fonc.2021.722754

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