Development of purification process for dual‐function recombinant human heavy‐chain ferritin by the investigation of genetic modification impact on conformation

Ferritin is a promising drug delivery platform and has been functionalized through genetic modifications. This work has designed and expressed a dual‐functional engineered human heavy‐chain ferritin (HFn) with the inserted functional peptide PAS and RGDK to extend half‐life and improve tumor targete...

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Detalles Bibliográficos
Autores principales: Yin, Shuang, Zhang, Bingyang, Lin, Jianying, Liu, Yongdong, Su, Zhiguo, Bi, Jingxiu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8518560/
https://www.ncbi.nlm.nih.gov/pubmed/34690634
http://dx.doi.org/10.1002/elsc.202000105

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8518560/
https://www.ncbi.nlm.nih.gov/pubmed/34690634
http://dx.doi.org/10.1002/elsc.202000105

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