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Development of a 3D‐printed single‐use separation chamber for use in mRNA‐based vaccine production with magnetic microparticles

Laboratory protocols using magnetic beads have gained importance in the purification of mRNA for vaccines. Here, the produced mRNA hybridizes specifically to oligo(dT)‐functionalized magnetic beads after cell lysis. The mRNA‐loaded magnetic beads can be selectively separated using a magnet. Subseque...

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Detalles Bibliográficos
Autores principales: Wommer, Lars, Meiers, Patrick, Kockler, Isabelle, Ulber, Roland, Kampeis, Percy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8518576/
https://www.ncbi.nlm.nih.gov/pubmed/34690630
http://dx.doi.org/10.1002/elsc.202000120