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Development of a 3D‐printed single‐use separation chamber for use in mRNA‐based vaccine production with magnetic microparticles
Laboratory protocols using magnetic beads have gained importance in the purification of mRNA for vaccines. Here, the produced mRNA hybridizes specifically to oligo(dT)‐functionalized magnetic beads after cell lysis. The mRNA‐loaded magnetic beads can be selectively separated using a magnet. Subseque...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8518576/ https://www.ncbi.nlm.nih.gov/pubmed/34690630 http://dx.doi.org/10.1002/elsc.202000120 |