A Minimal Load‐and‐Lock Ru(II) Luminescent DNA Probe

Threading intercalators bind DNA with high affinities. Here, we describe single‐molecule studies on a cell‐permeant luminescent dinuclear ruthenium(II) complex that has been previously shown to thread only into short, unstable duplex structures. Using optical tweezers and confocal microscopy, we sho...

Descripción completa

Detalles Bibliográficos
Autores principales: Newton, Matthew D., Fairbanks, Simon D., Thomas, Jim A., Rueda, David S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8518596/
https://www.ncbi.nlm.nih.gov/pubmed/34378843
http://dx.doi.org/10.1002/anie.202108077

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8518596/
https://www.ncbi.nlm.nih.gov/pubmed/34378843
http://dx.doi.org/10.1002/anie.202108077

Ejemplares similares