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Bletinib ameliorates neutrophilic inflammation and lung injury by inhibiting Src family kinase phosphorylation and activity

BACKGROUND AND PURPOSE: Neutrophil overactivation is crucial in the pathogenesis of acute lung injury (ALI). Bletinib (3,3′‐dihydroxy‐2′,6′‐bis(p‐hydroxybenzyl)‐5‐methoxybibenzyl), a natural bibenzyl, extracted from the Bletilla plant, exhibits anti‐inflammatory, antibacterial, and antimitotic effec...

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Detalles Bibliográficos
Autores principales: Kao, Ting‐I, Chen, Po‐Jen, Wang, Yi‐Hsuan, Tseng, Hsin‐Hui, Chang, Shih‐Hsin, Wu, Tian‐Shung, Yang, Sien‐Hung, Lee, Yen‐Tung, Hwang, Tsong‐Long
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8518616/
https://www.ncbi.nlm.nih.gov/pubmed/34131920
http://dx.doi.org/10.1111/bph.15597