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Bletinib ameliorates neutrophilic inflammation and lung injury by inhibiting Src family kinase phosphorylation and activity
BACKGROUND AND PURPOSE: Neutrophil overactivation is crucial in the pathogenesis of acute lung injury (ALI). Bletinib (3,3′‐dihydroxy‐2′,6′‐bis(p‐hydroxybenzyl)‐5‐methoxybibenzyl), a natural bibenzyl, extracted from the Bletilla plant, exhibits anti‐inflammatory, antibacterial, and antimitotic effec...
Autores principales: | Kao, Ting‐I, Chen, Po‐Jen, Wang, Yi‐Hsuan, Tseng, Hsin‐Hui, Chang, Shih‐Hsin, Wu, Tian‐Shung, Yang, Sien‐Hung, Lee, Yen‐Tung, Hwang, Tsong‐Long |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8518616/ https://www.ncbi.nlm.nih.gov/pubmed/34131920 http://dx.doi.org/10.1111/bph.15597 |
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