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Alpha Synuclein only Forms Fibrils In Vitro when Larger than its Critical Size of 70 Monomers
The aggregation of α‐synuclein into small soluble aggregates and then fibrils is important in the development and spreading of aggregates through the brain in Parkinson's disease. Fibrillar aggregates can grow by monomer addition and then break into fragments that could spread into neighboring...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8518629/ https://www.ncbi.nlm.nih.gov/pubmed/34383993 http://dx.doi.org/10.1002/cbic.202100285 |