Biomimetic Iron Complex Achieves TET Enzyme Reactivity

The epigenetic marker 5‐methyl‐2′‐deoxycytidine (5mdC) is the most prevalent modification to DNA. It is removed inter alia via an active demethylation pathway: oxidation by Ten‐Eleven Translocation 5‐methyl cytosine dioxygenase (TET) and subsequent removal via base excision repair or direct demodifi...

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Detalles Bibliográficos
Autores principales: Schmidl, David, Jonasson, Niko S. W., Korytiaková, Eva, Carell, Thomas, Daumann, Lena J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8518650/
https://www.ncbi.nlm.nih.gov/pubmed/34181314
http://dx.doi.org/10.1002/anie.202107277

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8518650/
https://www.ncbi.nlm.nih.gov/pubmed/34181314
http://dx.doi.org/10.1002/anie.202107277

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